Assignments within sub-expressions are hard to spot and therefore make the code less readable.
It is also a common mistake to write = when == was meant.
Ideally, expressions should not have side-effects.
doSomething(i = 42);
i = 42; doSomething(i);
or
doSomething(i == 42); // Perhaps in fact the assignment operator was expected
Assignments in while statement conditions, and assignments enclosed in relational expressions are allowed.